BDBM32203 8-quinolinol::CHEMBL310555::US10005735, Table 1.7::US9394254, 6::cid_1923::oxine::quinolin-8-ol

SMILES Oc1cccc2cccnc12

InChI Key InChIKey=MCJGNVYPOGVAJF-UHFFFAOYSA-N

Data  1 KI  24 IC50  1 EC50

PDB links: 3 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 32203   

TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay

LigandBDBM32203(8-quinolinol | CHEMBL310555 | US10005735, Table 1....)Copy SMILESCopy InChI

Affinity DataIC50:  5.00E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLMCE
KEGGMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails PCBioAssay
Copy BDB DOI